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Year Number of Results
2017 1
2018 1
2019 6
2020 1
2021 3
2022 2
2023 7
2024 1

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19 results

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Page 1
Vascular cells improve functionality of human cardiac organoids.
Voges HK, Foster SR, Reynolds L, Parker BL, Devilée L, Quaife-Ryan GA, Fortuna PRJ, Mathieson E, Fitzsimmons R, Lor M, Batho C, Reid J, Pocock M, Friedman CE, Mizikovsky D, Francois M, Palpant NJ, Needham EJ, Peralta M, Monte-Nieto GD, Jones LK, Smyth IM, Mehdiabadi NR, Bolk F, Janbandhu V, Yao E, Harvey RP, Chong JJH, Elliott DA, Stanley EG, Wiszniak S, Schwarz Q, James DE, Mills RJ, Porrello ER, Hudson JE. Voges HK, et al. Among authors: needham ej. Cell Rep. 2023 May 30;42(5):112322. doi: 10.1016/j.celrep.2023.112322. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37105170 Free article.
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Zhao JH, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman ÅK, Kalnapenkis A, Enroth S, Cozzetto D, Digby-Bell J, Marten J, Folkersen L, Herder C, Jonsson L, Bergen SE, Gieger C, Needham EJ, Surendran P; Estonian Biobank Research Team; Paul DS, Polasek O, Thorand B, Grallert H, Roden M, Võsa U, Esko T, Hayward C, Johansson Å, Gyllensten U, Powell N, Hansson O, Mattsson-Carlgren N, Joshi PK, Danesh J, Padyukov L, Klareskog L, Landén M, Wilson JF, Siegbahn A, Wallentin L, Mälarstig A, Butterworth AS, Peters JE. Zhao JH, et al. Among authors: needham ej. Nat Immunol. 2023 Sep;24(9):1540-1551. doi: 10.1038/s41590-023-01588-w. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563310 Free PMC article.
Personalized phosphoproteomics identifies functional signaling.
Needham EJ, Hingst JR, Parker BL, Morrison KR, Yang G, Onslev J, Kristensen JM, Højlund K, Ling NXY, Oakhill JS, Richter EA, Kiens B, Petersen J, Pehmøller C, James DE, Wojtaszewski JFP, Humphrey SJ. Needham EJ, et al. Nat Biotechnol. 2022 Apr;40(4):576-584. doi: 10.1038/s41587-021-01099-9. Epub 2021 Dec 2. Nat Biotechnol. 2022. PMID: 34857927
Illuminating the dark phosphoproteome.
Needham EJ, Parker BL, Burykin T, James DE, Humphrey SJ. Needham EJ, et al. Sci Signal. 2019 Jan 22;12(565):eaau8645. doi: 10.1126/scisignal.aau8645. Sci Signal. 2019. PMID: 30670635 Review.
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance.
Fazakerley DJ, van Gerwen J, Cooke KC, Duan X, Needham EJ, Díaz-Vegas A, Madsen S, Norris DM, Shun-Shion AS, Krycer JR, Burchfield JG, Yang P, Wade MR, Brozinick JT, James DE, Humphrey SJ. Fazakerley DJ, et al. Among authors: needham ej. Nat Commun. 2023 Feb 18;14(1):923. doi: 10.1038/s41467-023-36549-2. Nat Commun. 2023. PMID: 36808134 Free PMC article.
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Yang Sun YB, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo JM, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: needham ej. Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. Stem Cell Reports. 2023. PMID: 37315523 Free PMC article.
Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Zhao JH, Stacey D, Eriksson N, Macdonald-Dunlop E, Hedman ÅK, Kalnapenkis A, Enroth S, Cozzetto D, Digby-Bell J, Marten J, Folkersen L, Herder C, Jonsson L, Bergen SE, Gieger C, Needham EJ, Surendran P; Estonian Biobank Research Team; Paul DS, Polasek O, Thorand B, Grallert H, Roden M, Võsa U, Esko T, Hayward C, Johansson Å, Gyllensten U, Powell N, Hansson O, Mattsson-Carlgren N, Joshi PK, Danesh J, Padyukov L, Klareskog L, Landén M, Wilson JF, Siegbahn A, Wallentin L, Mälarstig A, Butterworth AS, Peters JE. Zhao JH, et al. Among authors: needham ej. Nat Immunol. 2023 Nov;24(11):1960. doi: 10.1038/s41590-023-01635-6. Nat Immunol. 2023. PMID: 37679551 Free PMC article. No abstract available.
Targets mapped for almost all human kinase enzymes.
Humphrey SJ, Needham EJ. Humphrey SJ, et al. Among authors: needham ej. Nature. 2023 Jan;613(7945):637-638. doi: 10.1038/d41586-022-04583-7. Nature. 2023. PMID: 36631581 No abstract available.
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells.
Recasens A, Humphrey SJ, Ellis M, Hoque M, Abbassi RH, Chen B, Longworth M, Needham EJ, James DE, Johns TG, Day BW, Kassiou M, Yang P, Munoz L. Recasens A, et al. Among authors: needham ej. Cell Death Discov. 2021 Apr 16;7(1):81. doi: 10.1038/s41420-021-00456-6. Cell Death Discov. 2021. PMID: 33863878 Free PMC article.
An integrative systems genetic analysis of mammalian lipid metabolism.
Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, Peng KY, Lee R, Jayawardana K, Pan C, Mellett NA, Weir JM, Lazarus R, Lusis AJ, Meikle PJ, James DE, de Aguiar Vallim TQ, Drew BG. Parker BL, et al. Among authors: needham ej. Nature. 2019 Mar;567(7747):187-193. doi: 10.1038/s41586-019-0984-y. Epub 2019 Feb 27. Nature. 2019. PMID: 30814737 Free PMC article.
19 results